Summary:
An HPLC method for the simultaneous determination of the glucocorticoids betamethasone and dexamethasone is described. The method based on the separation of these compounds using a binary watertetrahyddrofuran mobile phase and a reversed-phase Hypersil C18 column, was applied to the determination of betamethasone and dexamethasone in tablets.
Keywords: Column liquid chromatography; Glucocorticoids; Betamethasone and dexamethasone; Pharmaceuticals; Tablet preparations;
JCR Impact Factor and WoS quartile: 1,700 - Q4 (2022)
DOI reference:
https://doi.org/10.1007/BF02268276
Published on paper: November 1994.
Citation:
A. Santos-Montes, A.I. Gasco-Lopez, R. Izquierdo-Hornillos, Simultaneous determination of dexamethasone and betamethasone in pharmaceuticals by reversed-phase HPLC. Chromatographia. Vol. 39, nº. 9-10, pp. 539 - 542, November 1994.
